PASTENE, E.; HEBEL, S.; GARCÍA, A.; VIZCARRA, L.; AVELLO, M.; PARADA, V.; BUSTAMANTE, L,; PINUER, L.; ARANDA, M.; TORRES, E.; URBINA, A.:
Pharmacology online 2014- vol.2 Supplementary Issue. 23º SILAE Congress, Abstracts Book, poster presentation p 226.
Abstract
Helicobacter pylori (Hp) is a pathogen whose global prevalence reach 50%, is involved in gastric diseases such as gastritis, duodenal ulcer and gastric cancer. To eradicate this bacterium, antibiotic triple therapy is used, which may show side effects associated with abandonment and failure. This is a critical factor because could promote selection of antibiotic resistance. Therefore, there is a constant search for new molecules with safer and selective profile against this pathogen. The aim of this work was to continue to identification of bioactive molecules from extracts of the edible petiole of Gunnera tinctoria (nalca), based on their ability to inhibit the growth of H. pylori.